1. Installation

neuroCombat can be installed in R by typing the following commands:


This also required to have neuroCombat installed:


2. Simulated dataset

The neuroCombatData package contains a dataset called seCorticalThickness

that contains simulated multi-site cortical thickness measurements (263 subjects across 9 sites).Data were simulated based on a subset of the UCSF FreeSurfer cross-sectional cortical thickness processed data.The goal of the simulation was to create a dataset that mimics both the technical variability and biological variability observed in a in real-world study. Imaging features (ROIs) correspond to the featured measured in the FreeSurfer software (v6.0).

The data can be accessed using the following code: